Biokmod HELP
ELEMENT is the symbol of the element
λ
is the radioactive decay constant, in day-1. If you know the half-life T in place of λ, as λ = Log[t]/T you can write: Log[2]/T, ej.: For T = 8.2 year, then write: Log[2]/(365.24*8.2) .
IntakeWay choose "Injection" or "Ingestion" or "Inhalation";
AMAD (Activity Median Aerodynamic Diameter): (only by Inhalation) choose the value which you wish (usually AMAD = 5). Then the program will select the appropriated Initial fractional Deposition (IFD) values.
Class (only by Inhalation) choose: F or M or S. Then the program will select the appropriate fractional rate of absorption.
f1: fraction from GI (SI) to Blood. If you has chosen a Class (by inhalation), them in f1 will appear the appropiaded values for the element selected according to ICRP, but you can change this value.
IntakeType choose "Acute" or "Constant", "Continuous" or "MultiInputs";
- "Acute" is a single intake at t = 0,
- "Constant" (or Chronic) means a constant daily intake (all days the same).
- "Continuous" is an intake variable in the time, ej: 0.1 Exp[- 0.02 t] (not available for inhalation).
- "MultiInputs" are multi single (or acute) inputs.
Intake.- The input format depends on the "Intake type" chosen.
- For "Acute" write the number of Bq in t = 0
- For "Constant" write the number of Bq/day.
- For "Continuous" write {f(t) , t} where f(t) is the input functions. Ej.: {0.1 Exp[- 0.02 t], t}
- For "MultiInputs" write {{I0, t0}, {I1, t1}, .... {Ij, tj},…,{In, tn}} (where Ij, represents the intake the day tj, and t1<t2<..<tn ). Ej.: {{3, 0},{7, 3}}. The retention is given as function of t after the last intake (tn=0); Note: The length of the list {{I0, t0},....., {In, tn}} can be hundred of elements, it will be computed in a few seconds. It can be copied from a ASCII standard program (ej: Notebook)
Output Report choose: "IRD (Retention Fraction)" or "Retention Functions" or "GraphicsReport" , or "CompartmentContent" or "Disintegrations".
- "IRD (Retention Fraction)" gives the Lungs (only by inhation) and whole body retention , daily urine and faecal excretion for different days.
- "Retention Functions" gives the Lungs (only by inhalation) and whole body retention , daily urine and faecal excretion as function of t.
- "GraphicsReport" gives the graphics representation as function of time of the Lungs retention (only by inhalation), and the daily urine and faecal excretion, from 0 to t (chosen with"Time").
- "CompartmentContent" gives the retention in each compartment of the model as function of t.
- "Disintegrations" gives the total disintegration accumulated at time t (that is: Us or SA values).These values can be used to calculate the Dose Conversion Factors (DCFs). You will need the Dose Factors (DFs), they can be obtained from RADAR
Time t always in days. The meaning depends on the "Intake type" chosen.
- For "Acute" means time after the intake. Write t (symbolic solution) or the numeric number of days (ej: 2 ).
- For "Constant" means time after starting the intake. Write t (symbolic solution) or the numeric number of days (ej: 2 )
- For "Continuous" means time after starting the intake. Write t (symbolic solution) or the numeric number of days (ej: 2 )
- For "MultiInputs" means the time after last intake. Write t (symbolic solution) or the numeric number of days (ej: 2 ).
Note: If in Output Report you has chosen "GraphicsReport" or "IRD (Retention Fraction)" must be chosen a numeric value for Time
CompartNumbers and TransferRates options.- If "True" gives a report where is indicated the relation between the number and the name of compartments, and also the Tranfer Rates. It a good idea to choose this option if in Output Report has been chosen "CompartmentContent" or "Disintegration".